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Targets Recommended: c-RET

123

抑制剂 & 化合物

15

天然产物

1808

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8467 RET V804M-IN-1

RETV804M kinase inhibitor,LUN09945

c-RET Apoptosis; Tyrosine Kinase/Adaptors
RET V804M-IN-1 (RETV804M kinase inhibitor) 是一种 wt-RET 选择性的RETV804M 激酶抑制剂,其IC50=20 nM。
T72060 Myosin V-IN-1

Myosin Cytoskeletal Signaling
Myosin V-IN-1是一种有效且具有选择性的 Myosin V 抑制剂,Ki 值为 6 μM。Myosin V-IN-1 抑制肌动蛋白 V 发生作用, 通过选择性抑制肌动球蛋白复合物释放 ADP 来减缓肌动蛋白激活的肌球蛋白 V ATP 酶。
T13473 αvβ1 integrin-IN-1

Integrin Cytoskeletal Signaling
αvβ1 integrin-IN-1是一种强效且具有选择性的αvβ1整合素抑制剂(IC50为0.63 nM),具有抗纤维化作用。
T8316 1V209

TLR7 agonist T7

TLR Immunology/Inflammation
1V209 (TLR7 agonist T7) 是一种 Toll 样受体 7 (TLR7) 激动剂,可与各种多糖缀合,以改善其水溶性,增强功效并保持低毒性,具有抗肿瘤作用。
T8579 Nav1.8-IN-1

5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208

Sodium Channel Membrane transporter/Ion channel
Nav1.8-IN-1 (CHEMBL1270208) 是一种有效的 Na(v)1.8 钠通道抑制剂,可用于研究精神性疼痛及炎症性疼痛。
T78451 Patent Blue V

Acid blue 1

Patent Blue V(Acid blue 1)是一款应用于眼科的新型生物染料,特别是在进行视网膜切除手术时,用以染色以便去除内限制膜(ILM)。该染料在玻璃体视网膜手术中确保了对视网膜结构的有效标记,从而实现精确去除。光谱分析揭示,Patent Blue V在450 nm以下和600 nm以上具有强烈的吸收特性,展现蓝绿色。此外,它亦作为淋巴管造影术中的追踪剂,在染色活检手术中使用以助于淋巴结的切除。
T40243 αvβ5 integrin-IN-1

αvβ5 integrin-IN-1 is a first potent and selective αvβ5 integrin inhibitor (p IC 50 = 8.2) .
T124032 V1 iridoid

V1 iridoid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124032。
T126501 Xanthone V1a

Xanthone V1a 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126501
T73625 αvβ1 integrin-IN-1 TFA

αvβ1integrin-IN-1 TFA (Compound C8) 为高效的αvβ1整合素选择性抑制剂,IC50值仅为0.63 nM,具备显著的抗纤维化能力。
T61820 Ar-V7-IN-1

Ar-V7-IN-1 is a highly potent inhibitor specifically targeting Ar-V7, a splice variant of the androgen receptor that exhibits hormone-independent behavior. Its development shows promise for researching various indications, notably cancers such as prostate cancer[1].
T61110 UC-1V150

UC-1V150 is a distinct TLR7 agonist, which activates cellular immune responses and exhibits anti-tumor effects. It also serves as a precursor for the synthesis of ISAC molecules, known as immune-stimulating antibody conjugates [1] [2].
T79792 αvβ1 integrin-IN-2

Integrin Cytoskeletal Signaling
αvβ1integrin-IN-2(compound 32)作为整合素ανβ1与α5β1的抑制剂,展现出高效性,其IC50值分别为0.9 nM和33 nM。此外,该化合物对其他整合素亦有抑制作用,其IC50分别为380 nM(ανβ3)、280 nM(ανβ5)、230 nM(ανβ6)、87 nM(ανβ8)。
T37369 Amyloid-β (1-8, A2V) Peptide

Amyloid-β (1-8, A2V) Peptide

Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Aβ (1-40) (Aβ40) A2V peptide increases the production of Aβ and the rate and amount of amyloid fibril formation in vitro, effects that can be reduced by coincubation with wild-type Aβ40. Aβ40 and Aβ42 levels are increased in CHO ...
T64174 Vasopressin V2 receptor antagonist 1

Vasopressin V2 receptor antagonist 1 (Compound 4g) 是一种 vasopressin V2receptor (V2R) 拮抗剂 (Ki: 3.8 nM)。Vasopressin V2 receptor antagonist 1 可以用于研究常染色体显性多囊肾病 (ADPKD)。
T76080 Human PD-L1 inhibitor V

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
V (human PD-L1 inhibitor) 是一种与human PD-1 protein结合的肽,具有3.32 μM的Kd值,能有效抑制PD-1/PD-L1之间的相互作用。
T63448 BRAF V600E/CRAF-IN-1

BRAF V600E/CRAF-IN-1 是 BRAFV600E/CRAF 的有效抑制剂。BRAF V600E/CRAF-IN-1 能够作用于 HCT-116 结肠癌细胞的 G0/G1 期,使细胞周期停滞,并导致细胞凋亡。BRAF V600E/CRAF-IN-1 表现出潜力进行癌症疾病的研究。
T76080L Human PD-L1 inhibitor V TFA

HumanPD-L1inhibitor V TFA 是一种humanPD-1protein 结合肽,Kd 值为 3.32 μM,可抑制人PD-1/PD-L1的结合。
T74410 PROTAC AR-V7 degrader-1

PROTACs PROTAC
PROTACAR-V7 degrader-1 (Compound 6)为一种口服有效的,选择性针对AR-V7的降解剂,DC50值为0.32 µM,其作用机制主要是通过VHL E3连接酶将其招募至雄激素受体DNA结合域(AR DBD)。此外,PROTACAR-V7 degrader-1在表达AR-V7的22Rv1细胞系中展现出了活性,EC50值为0.88 µM。
T80249 Epsilon-V1-2, Cys-conjugated

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
Epsilon-V1-2, Cys-conjugated 是 εPKC 特异性抑制剂,通过阻断 εPKC 与 εRACK 锚定蛋白之间的相互作用,抑制 εPKC 易位及 MARCKS 磷酸化,从而表现生物活性。该肽将半胱氨酸残基接到 C 末端,以形成与载体蛋白的 SS 键。当序列 N 末端为谷氨酰胺 (Q) 或谷氨酸 (E) 时,肽可自发生成焦谷氨酰 (pGlu)。Q或E到pGlu的转化属于自然过程,并且pGlu的疏水性γ-内酰胺环对提高肽对胃肠道蛋白酶的稳定性起关键作用。在 HPLC 分析中,焦谷氨酰肽作为肽纯度的一部分进行检测,视为这类肽的典型子集。
T35827 Epsilon-V1-2

PKCε Inhibitor Peptide,Protein Kinase Cɛ Inhibitor Peptide,ɛV1-2

Protein kinase C (PKC ) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation.[1] PKC inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKC .[2] It selectively and reversibly inhibits the translocation of PKC to intracellular membrane...
T60047L V-0219 hydrochloride

V-0219 hydrochloride(878453-71-5 Free base)

Glucagon Receptor GPCR/G Protein
V-0219 hydrochloride 是一种具有口服活性的 glucagon-like peptide-1 receptor (GLP-1R) 正向别构调节剂 (PAM)。V-0219 能被用于肥胖相关糖尿病的研究。
T7371 1-Naphthyl PP1 hydrochloride

1-叔丁基-3-(1-萘基)-1H-吡唑并[3,4-D]嘧啶-4-胺盐酸盐,1-NA-PP 1 hydrochloride

Src Angiogenesis; Tyrosine Kinase/Adaptors
1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) 是选择性的 src 家族激酶抑制剂,能够抑制 v-Src (IC50:1.0 μM)、c-Fyn (IC50:0.6 μM)、c-Abl (IC50:0.6 μM)、CDK2 (IC50:18 μM)、CAMK II (IC50:22 μM)。
T20984 Lumogallion

荧光镓,4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid

Others Others
Lumogallion (4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid) 是一种偶氮试剂,用于测定金属离子,如研究 V、Fe 和 Al。
T3935 1-Naphthyl PP1

4 -氨基- 1 -叔丁基- 3 -(1' -萘基)吡唑并[3,4 - D]嘧啶,1-NA-PP 1

Src Angiogenesis; Tyrosine Kinase/Adaptors
1-Naphthyl PP1 (1-NA-PP 1) 是选择性的src 家族激酶抑制剂,能够抑制 v-Src (IC50:1.0 μM)、c-Fyn (IC50:0.6 μM)、c-Abl (IC50:0.6 μM)、CDK2 (IC50:18 μM) 和 CAMK II (IC50:22 μM)。
T60122 Aldometanib

Compound IA-47 (Br- base 2246625-81-8)

Others; AMPK Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
Aldometanib (LXY-05-029) 是一种具有口服活性的醛缩酶抑制剂,可以阻止FBP 与v-ATPase 相关的醛缩酶结合,并激活溶酶体 AMPK 。Aldometanib 可用于代谢稳态的研究。
T8461 SKI V

Apoptosis; PI3K; S1P Receptor Apoptosis; GPCR/G Protein; PI3K/Akt/mTOR signaling
SKI V 是一种非竞争性非脂质鞘氨醇激酶抑制剂,对 GST-hSK 的IC50为 2 μM。 它减少有丝分裂的第二信使鞘氨醇-1-磷酸的形成,可诱导细胞凋亡并具有抗肿瘤活性。它还抑制PI3K,对 hPI3k 的IC50为 6 μM。
T6289 Dovitinib

TKI258,多韦替尼,CHIR-258,度维替尼

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。
T6479 Dovitinib lactate hydrate

Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂,抑制 FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T2153 1-NM-PP1

PP1 Analog II,1 nM-PP1

Serine/threonin kinase; CDK; Src Angiogenesis; Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
1-NM-PP1 (PP1 Analog II) 是一种有效的Src 家族激酶抑制剂,是一种细胞渗透性 PP1 类似物,对 v-Src-as1 与 c-Fyn-as1 的IC50值分别为 4.3 nM、3.2 nM。
TP1913L1 BA 1 acetate(183241-31-8 free base)

Bombesin Receptor GPCR/G Protein
BA 1 acetate(183241-31-8 free base) 是一种有效的铃蟾肽受体激动剂(BB1、BB2 和 BB3 的 IC50 值分别为 0.26、1.55 和 2.52 nM)。它增强肥胖和糖尿病原发性肌细胞中的葡萄糖转运,还可在体外刺激 NCI-H1299 肺癌细胞增殖。
T36944 Ara-G

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Ara-G 是一种脱氧鸟苷 (GdR) 类似物和核苷类似物,可被 T 淋巴谱系细胞迅速转化为其相应的阿拉伯糖基鸟嘌呤核苷酸三磷酸 (araGTP),从而抑制 DNA 合成和对 T 淋巴母细胞的选择性体外毒性细胞系以及来自 T 细胞急性淋巴细胞白血病 (ALL) 患者的新鲜分离的白血病细胞。
T80172 Stromatoxin 1

Potassium Channel Membrane transporter/Ion channel
Stromatoxin 1是从狼蛛中分离出的肽类钾通道抑制剂,特异性地抑制K(V)2.1、K(V)2.2、K(V)4.2和K(V)2.1/9.3通道。其中,K(V)2.1和K(V)2.2通道亚基对大鼠肌源性和神经源性膀胱平滑肌(UBSM)的收缩起关键调控作用,然而K(V)4.2则不参与此作用。
T73080 (R)-V-0219

(R)-V-0219 是 V-0219 的对映异构体。V-0219 是一种口服有效的 GLP 受体 (GLP Receptor,GLP-1R) 的正变构调节剂 (PAM)。(R)-V-0219 可激活表达 hGLP-1R 的 HEK 细胞中的钙流。
T74264 (R)-V-0219 hydrochloride

(R)-V-0219 hydrochloride 是 V-0219 的对映异构体。V-0219 是一种口服有效的 GLP 受体 (GLP Receptor,GLP-1R) 的正变构调节剂 (PAM)。(R)-V-0219 hydrochloride 可激活表达 hGLP-1R 的 HEK 细胞中的钙流。
T74265 (S)-V-0219 hydrochloride

(S)-V-0219 hydrochloride 是 V-0219 的对映异构体。V-0219 是一种口服有效的 GLP 受体 (GLP Receptor,GLP-1R) 的正变构调节剂 (PAM)。(S)-V-0219 hydrochloride 可激活表达 hGLP-1R 的 HEK 细胞中的钙流。(S)-V-0219 hydrochloride 具有口服活性,可改善小鼠体内的高葡萄糖水平,并抑制禁食小鼠的进食行为。
T81892 M351-110

M351-110为T细胞活化V域免疫球蛋白抑制因子(TCR V域)激动剂,应用于癌症研究领域。
T61421 LUF7244

LUF7244, a selective allosteric modulator of K v 11.1 channels, effectively suppresses early afterdepolarizations and holds potential for anti-arrhythmia research [1].
T68693 AZ12099548

AZ12099548 is a transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist.
T73081 (S)-V-0219

(S)-V-0219 是 V-0219 的对映异构体。V-0219 是一种口服有效的 GLP 受体 (GLP Receptor,GLP-1R) 的正变构调节剂 (PAM)。(S)-V-0219 可激活表达 hGLP-1R 的 HEK 细胞中的钙流。(S)-V-0219 具有口服活性,可改善小鼠体内的高葡萄糖水平,并抑制禁食小鼠的进食行为。
T61026 CaV1.3 antagonist-1

CaV1.3 antagonist-1 是一种具有帕金森病研究潜力的环戊基衍生物。CaV1.3 antagonist-1 抑制 CaV1.3 LTCC 的效率比 CaV1.2 LTCC 高 600 多倍。CaV1.3 antagonist-1 是一种有效的、高度选择性的 CaV1.3L 型钙通道拮抗剂,IC50值为 1.7 μM。
T60047 V-0219

Glucagon Receptor GPCR/G Protein
V-0219 是 GLP-1 的正变构调节剂,可用于肥胖相关糖尿病的研究。
T82820 Bremzalerbart

Bremzalerbart为针对主要桦树花粉过敏原Bet v 1-A的BETVIA的人源IgG4单克隆抗体。
T80178 Dc1a

Sodium Channel Membrane transporter/Ion channel
Dc1a是一种从沙漠灌木蜘蛛Diguetia canities分离的毒素,有效促进德国小蠊Nav通道(BgNav1)的开放。
T75883 Agitoxin-2 TFA

Agitoxin-2 TFA 是K+通道的阻断剂,其对 mKV1.3 和 mKV1.1 的IC50值分别为 201 pM 和 144 pM。
T78285 Sofituzumab

MMUC 1206A

Sofituzumab(MMUC 1206A)是一款针对MUC16的重组人源化V-kappa型单克隆抗体。
T80451 Ceratotoxin-2

CcoTx2,β-TRTX-cm1b

Sodium Channel Membrane transporter/Ion channel
Ceratotoxin-2 (CcoTx2) 为针对电压门控的钠通道阻滞剂,显示对Nav1.2/β1和Nav1.3/β1的强效选择性,其IC50值分别为8 nM及88 nM。
T82946 Atisnolerbart

Atisnolerbart为一种靶向BETVIA的人源IgG4抗体,其中BETVIA指的是桦树花粉过敏原Bet v 1-A的主要成分。
T80494 Tap1a

TRTX-Tap1a,Theraphotoxin-Tap1a,µ/ω-TRTX-Tap1a

Sodium Channel Membrane transporter/Ion channel
Tap1a (Theraphotoxin-Tap1a) 是抑制sodium channels的一种蜘蛛毒液肽,其对Nav1.7的IC50为80 nM,对Nav1.1为301 nM,显示出缓解疼痛的潜能。
T80551 Calpain inhibitor V

Mu-Val-HPh-FMK

Antibiotic Microbiology/Virology
Calpain inhibitor V (Mu-Val-HPh-FMK) 为具抗衣原体活性的细胞渗透性不可逆钙蛋白酶抑制剂。

化合物

RET V804M-IN-1
Cat.No: T8467
Synonym: RETV804M kinase inhibitor,LUN09945
Target: c-RET
Myosin V-IN-1
Cat.No: T72060
Synonym:
Target: Myosin
αvβ1 integrin-IN-1
Cat.No: T13473
Synonym:
Target: Integrin
1V209
Cat.No: T8316
Synonym: TLR7 agonist T7
Target: TLR
Nav1.8-IN-1
Cat.No: T8579
Synonym: 5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208
Target: Sodium Channel
Patent Blue V
Cat.No: T78451
Synonym: Acid blue 1
Target:
αvβ5 integrin-IN-1
Cat.No: T40243
Synonym:
Target:
V1 iridoid
Cat.No: T124032
Synonym:
Target:
Xanthone V1a
Cat.No: T126501
Synonym:
Target:
αvβ1 integrin-IN-1 TFA
Cat.No: T73625
Synonym:
Target:
Ar-V7-IN-1
Cat.No: T61820
Synonym:
Target:
UC-1V150
Cat.No: T61110
Synonym:
Target:
αvβ1 integrin-IN-2
Cat.No: T79792
Synonym:
Target: Integrin
Amyloid-β (1-8, A2V) Peptide
Cat.No: T37369
Synonym: Amyloid-β (1-8, A2V) Peptide
Target:
Vasopressin V2 receptor antagonist 1
Cat.No: T64174
Synonym:
Target:
Human PD-L1 inhibitor V
Cat.No: T76080
Synonym:
Target: PD-1/PD-L1
BRAF V600E/CRAF-IN-1
Cat.No: T63448
Synonym:
Target:
Human PD-L1 inhibitor V TFA
Cat.No: T76080L
Synonym:
Target:
PROTAC AR-V7 degrader-1
Cat.No: T74410
Synonym:
Target: PROTACs
Epsilon-V1-2, Cys-conjugated
Cat.No: T80249
Synonym:
Target: PKC
Epsilon-V1-2
Cat.No: T35827
Synonym: PKCε Inhibitor Peptide,Protein Kinase Cɛ Inhibitor Peptide,ɛV1-2
Target:
V-0219 hydrochloride
Cat.No: T60047L
Synonym: V-0219 hydrochloride(878453-71-5 Free base)
Target: Glucagon Receptor
1-Naphthyl PP1 hydrochloride
Cat.No: T7371
Synonym: 1-叔丁基-3-(1-萘基)-1H-吡唑并[3,4-D]嘧啶-4-胺盐酸盐,1-NA-PP 1 hydrochloride
Target: Src
Lumogallion
Cat.No: T20984
Synonym: 荧光镓,4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid
Target: Others
1-Naphthyl PP1
Cat.No: T3935
Synonym: 4 -氨基- 1 -叔丁基- 3 -(1' -萘基)吡唑并[3,4 - D]嘧啶,1-NA-PP 1
Target: Src
Aldometanib
Cat.No: T60122
Synonym: Compound IA-47 (Br- base 2246625-81-8)
Target: Others, AMPK
SKI V
Cat.No: T8461
Synonym:
Target: Apoptosis, PI3K, S1P Receptor
Dovitinib
Cat.No: T6289
Synonym: TKI258,多韦替尼,CHIR-258,度维替尼
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib lactate hydrate
Cat.No: T6479
Synonym: Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
1-NM-PP1
Cat.No: T2153
Synonym: PP1 Analog II,1 nM-PP1
Target: Serine/threonin kinase, CDK, Src
BA 1 acetate(183241-31-8 free base)
Cat.No: TP1913L1
Synonym:
Target: Bombesin Receptor
Ara-G
Cat.No: T36944
Synonym:
Target: Nucleoside Antimetabolite/Analog
Stromatoxin 1
Cat.No: T80172
Synonym:
Target: Potassium Channel
(R)-V-0219
Cat.No: T73080
Synonym:
Target:
(R)-V-0219 hydrochloride
Cat.No: T74264
Synonym:
Target:
(S)-V-0219 hydrochloride
Cat.No: T74265
Synonym:
Target:
M351-110
Cat.No: T81892
Synonym:
Target:
LUF7244
Cat.No: T61421
Synonym:
Target:
AZ12099548
Cat.No: T68693
Synonym:
Target:
(S)-V-0219
Cat.No: T73081
Synonym:
Target:
CaV1.3 antagonist-1
Cat.No: T61026
Synonym:
Target:
V-0219
Cat.No: T60047
Synonym:
Target: Glucagon Receptor
Bremzalerbart
Cat.No: T82820
Synonym:
Target:
Dc1a
Cat.No: T80178
Synonym:
Target: Sodium Channel
Agitoxin-2 TFA
Cat.No: T75883
Synonym:
Target:
Sofituzumab
Cat.No: T78285
Synonym: MMUC 1206A
Target:
Ceratotoxin-2
Cat.No: T80451
Synonym: CcoTx2,β-TRTX-cm1b
Target: Sodium Channel
Atisnolerbart
Cat.No: T82946
Synonym:
Target:
Tap1a
Cat.No: T80494
Synonym: TRTX-Tap1a,Theraphotoxin-Tap1a,µ/ω-TRTX-Tap1a
Target: Sodium Channel
Calpain inhibitor V
Cat.No: T80551
Synonym: Mu-Val-HPh-FMK
Target: Antibiotic
Cat. No. Product Name Target Signaling Pathways
T4S0039 Baimaside

白麻苷,Quercetin-3-O-sophoroside,Quercetin 3-beta-D-sophoroside

Others Others
Baimaside (Quercetin-3-O-sophoroside) 是一种超氧阴离子的清除剂,分离自A. venetum 的花中。
T3915 Ginsenoside Ro

人参皂苷Ro,Chikusetsusaponin 5,Polysciasaponin P3,人参皂苷 Ro,Chikusetsusaponin V

Calcium Channel; Reductase; Prostaglandin Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
Ginsenoside Ro (Chikusetsusaponin V) 能降低 TXA2产量,较弱降低 COX-1 和 TXAS 活性,具有 Ca2+拮抗剂的抗血小板作用,IC50为 155 μM。
TN1103 Diphyllin

山荷叶素,二叶草素

ATPase; Proton pump; Influenza Virus; HIV Protease Membrane transporter/Ion channel; Microbiology/Virology; Proteases/Proteasome
Diphyllin 是一种从Justicia procumbens 中分离的芳基萘木脂素,是HIV-1的有效抑制剂,IC50 为 0.38 μM。它是V-ATPase 抑制剂,IC50值为 17 nM,可抑制人破骨细胞中的溶酶体酸化。它抑制NO 产生,IC50值为 50 μM ,具有抗癌和抗炎活性。
T81959 Lacto-N-fucopentaose V

LNFP V

Lacto-N-fucopentaose V (LNFP V)为新型五糖,主要存在于人乳及其他生物体液中的低聚糖。
TN1440 Beta-Hydroxyisovalerylshikonin

EGFR; Tyrosine Kinases; Prostaglandin Receptor; Src; AMPK; Fatty Acid Synthase Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Beta-hydroxyisovalerylshikonin 是分离自Lithospermium radix 的天然产物,具有抑制PTK 的作用, 对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。它对多种肿瘤细胞系均有抑制作用,可以高效诱导 NCI-H522 和 DMS114 细胞的死亡。
T81113 Sporidesmolide V

Sporidesmolide V为从Pithornyces chartarum培养物中分离得到的环缩肽类化合物。
TN5993 16-Desoxycucurbitacin V

3β,20S,25-Trihydroxycucurbita-5,23-dien-11-one

16-Desoxycucurbitacin V 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5993,CAS号为 2081098-85-1
T35758 Butyrolactone V

Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM).2,1 Butyrolactone V (227 and 454.1 μM) is also active against adult S. mansoni worms.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS radicals with IC50 values of 20.7 and 3.7 μM, respectively, in cell-free assays.3 Butyrolactone V also...
T79965 11-Oxoisomogroside V

Metabolism
11-Oxoisomogroside V(compound 3)是从罗汉果粗提物中分离的一种葫芦苷,能够激活PGC-1α的转录活性。荧光素酶实验表明,10 μM 和 20 μM 浓度的11-Oxoisomogroside V分别将荧光素酶活性提高至 133.79% 和 143.81%。
T75611 Tibesaikosaponin V

Tibesaikosaponin V 是一种三萜双糖苷,可从北柴胡 (Bupleurum chinense DC) 的根的甲醇提取物中分离得到。Tibesaikosaponin V (TKV) 是一种三萜双糖苷,可从 Bupleurum chinense DC 根的甲醇提取物中分离得到。Tibesaikosaponin V 抑制脂质积累和甘油三酯含量的发生,对脂肪细胞没有细胞毒性。Tibesaikosaponin V 抑制核转录因子的 mRNA 表达,例如过氧化物酶体增殖物激活受体 γ (PPARγ) 和 CCAAT/增强子结合蛋白 α (C/EBPα)。Tibesaikosaponin V 抑制 3T3-L1 前脂肪细胞分化。Tibesaikosaponin V 可用于肥胖及其相关代谢紊乱的研究。
T82764 Cd1a

β-TRTX-cd1a,β-Theraphotoxin-cd1a

Cd1a是从非洲蜘蛛Ceratogyrus darlingi中提取的β-毒素,具有调节钙离子通道的功能。它能够抑制人类的钙离子通道(Cav2.2)(IC50 2.6 μM)以及小鼠的钠离子通道(Nav1.7),有望用于开发治疗外周疼痛的药物。
T36000 3-Hydroxyterphenyllin

3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...
T38349 Talaromycesone A

Talaromycesone A is a fungal metabolite originally isolated fromTalaromyces.1It is active againstS. epidermidisand methicillin-resistantS. aureus(MRSA) bacteria (IC50s = 3.70 and 5.48 μM, respectively). Talaromycesone A inhibits acetylcholinesterase (AChE) in a cell-free assay (IC50= 7.49 μM for the human enzyme). 1.Wu, B., Ohlendorf, B., Oesker, V., et al.Acetylcholinesterase inhibitors from a marine fungus Talaromyces sp. strain LF458Mar. Biotechnol. (NY)17(1)110-119(2015)
T36295 Echistatin TFA

Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...
T36438 Sporogen-AO 1

Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO 1 is cytotoxic to HeLa, KB, and NCI H187 cancer cells (IC50s = 8.3, 9, and 5.1 μM, respectively).2,5It is active againstC. albicans(MIC = 4 mM).3 1.Tanaka, S., Wada, K., Marumo, S., et al.Structure of sporogen-ao 1, a sporogenic substance of Aspergillus oryzaeTetrahedron Lett.25(...

天然产物

Baimaside
Cat.No: T4S0039
Synonym: 白麻苷,Quercetin-3-O-sophoroside,Quercetin 3-beta-D-sophoroside
Target: Others
Ginsenoside Ro
Cat.No: T3915
Synonym: 人参皂苷Ro,Chikusetsusaponin 5,Polysciasaponin P3,人参皂苷 Ro,Chikusetsusaponin V
Target: Calcium Channel, Reductase, Prostaglandin Receptor
Diphyllin
Cat.No: TN1103
Synonym: 山荷叶素,二叶草素
Target: ATPase, Proton pump, Influenza Virus, HIV Protease
Lacto-N-fucopentaose V
Cat.No: T81959
Synonym: LNFP V
Target:
Beta-Hydroxyisovalerylshikonin
Cat.No: TN1440
Synonym:
Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase
Sporidesmolide V
Cat.No: T81113
Synonym:
Target:
16-Desoxycucurbitacin V
Cat.No: TN5993
Synonym: 3β,20S,25-Trihydroxycucurbita-5,23-dien-11-one
Target:
Butyrolactone V
Cat.No: T35758
Synonym:
Target:
11-Oxoisomogroside V
Cat.No: T79965
Synonym:
Target:
Tibesaikosaponin V
Cat.No: T75611
Synonym:
Target:
Cd1a
Cat.No: T82764
Synonym: β-TRTX-cd1a,β-Theraphotoxin-cd1a
Target:
3-Hydroxyterphenyllin
Cat.No: T36000
Synonym:
Target:
Talaromycesone A
Cat.No: T38349
Synonym:
Target:
Echistatin TFA
Cat.No: T36295
Synonym:
Target:
Sporogen-AO 1
Cat.No: T36438
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

V-set domain containing T cell activation ...

Cynomolgus,Rhesus HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPY-05525 Art v 1 Protein, Artemisia vulgaris, Recombinant (His)

Art v 1,Defensin like protein 1

Artemisia vulgaris HEK293 Cells
Art v 1 Protein, Artemisia vulgaris, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is Q84ZX5.1.
TMPH-00199 Bet v 1-A Protein, Betula pendula, Recombinant (His & SUMO)

Allergen Bet v I-A,Major pollen allergen Bet v<...

Betula pendula E. coli
May be a general steroid carrier protein. Bet v 1-A Protein, Betula pendula, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.4 kDa and the accession number is P15494.
TMPY-04552 AKT1 Protein, Human, Recombinant (His)

RAC-ALPHA,v-akt murine thymoma viral oncog...

Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac...
TMPY-05322 B7-H4 Protein, Mouse, Recombinant (His)

BC032925,B7h4,B7x,V-set domain containing T cell ac...

Mouse HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5.
TMPH-02310 ATP6V0D1 Protein, Human, Recombinant (GST)

V-ATPase 40 kDa accessory protein,ATP6D,32 kDa acce...

Human E. coli
ATP6V0D1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 67.3 kDa and the accession number is P61421.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-r...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-03219 VISTA Protein, Human, Recombinant (His)

DD1α,V-set immunoregulatory receptor,SISP<...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
TMPY-03524 B7-H4 Protein, Human, Recombinant (His)

PRO1291,B7X,B7H4,B7-H4,VCTN1<...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPY-02529 VNN1 Protein, Mouse, Recombinant (His)

vanin 1,V-1

Mouse HEK293 Cells
VNN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.4 kDa and the accession number is Q9Z0K8.
TMPY-02730 VNN1 Protein, Mouse, Recombinant (hFc)

V-1,vanin 1

Mouse HEK293 Cells
VNN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79 kDa and the accession number is Q9Z0K8.
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-01802 c-Kit Protein, Mouse, Recombinant (His)

SCO5,SCO1,Bs,Gsfsco1,v-kit Hardy-...

Mouse HEK293 Cells
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P05532-1.
TMPK-00737 EVA-1/MPZL2 Protein, Human, Recombinant (hFc)

Eva,Mpzl2,EVA-1,EVA ...

Human HEK293 Cells
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons. EVA-1/MPZL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecu...
TMPK-00738 EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc)

EVA 1,Mpzl2,Epithelial V-like ant...

Mouse HEK293 Cells
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons. EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecu...
TMPJ-00377 VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated

INCAM-100,Vascular cell adhesion protein <...

Human HEK293 Cells
VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation。
TMPY-02563 VSTM1 Protein, Human, Recombinant (hFc)

VSTM1,V-set and transmembrane dom...

Human HEK293 Cells
V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds of protein families, including immunoglobulin light and heavy chains, several T-cells such as CD2, CD4, CD80, and CD86, myelin membrane adhesion molecules, junction adhesion molecules (JAM), tyrosine-protein kinase receptors, and the programmed cell death protein1. VSTM1 Protein,...
TMPY-02555 VSTM1 Protein, Human, Recombinant (His)

SIRL-1,UNQ3033,MGC11916<...

Human HEK293 Cells
V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds of protein families, including immunoglobulin light and heavy chains, several T-cells such as CD2, CD4, CD80, and CD86, myelin membrane adhesion molecules, junction adhesion molecules (JAM), tyrosine-protein kinase receptors, and the programmed cell death protein1. VSTM1 Protein,...
TMPY-06352 ALDH1A3 Protein, Mouse, Recombinant (His)

RALDH3,ALDH6,aldehyde dehydrogenase 1 family, membe...

Mouse E. coli
ALDH1A3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 56.94 kDa and the accession number is Q9JHW9.
TMPY-02658 B7-H4 Protein, Mouse, Recombinant (hFc)

B7h4,BC032925,B7x,B7s1,V-set domain contai...

Mouse HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q7TSP5.
TMPJ-00854 ETS1 Protein, Human, Recombinant (His)

V-ets Erythroblastosis Virus E26 Oncogene ...

Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPY-03487 NRAS Protein, Human, Recombinant (His)

NS6,NCMS,CMNS,neuroblastoma RAS viral (v-r...

Human E. coli
NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL6, a promyelocytic leukemia line. The mammalian ras gene family consists of the Harvey and Kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1), and the N-ras gene. They differ significantly only in the C-terminal 4 amino acids...
TMPY-00501 VISTA Protein, Human, Recombinant (hFc)

DD1α,SISP1,C10orf54,DD1a...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is AAH20568.1.
TMPY-05184 VISTA Protein, Human, Recombinant (His), Biotinylated

DD1alpha,VISTA,B7H5,V-set immunor...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
TMPY-06894 VISTA Protein, Human, Recombinant (His & Avi), Biotinylated

GI24,DD1alpha,PP2135,PD-1H,V<...

Human HEK293 Cells
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 kDa and the accession number is AAH20568.1.
TMPJ-00933 PRDX5 Protein, Human, Recombinant (His)

Antioxidant enzyme B166,Alu corepressor 1,...

Human HEK293 Cells
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/a...
TMPY-05080 B7-H4 Protein, Human, Recombinant (mFc)

B7H4,VCTN1,V-set domain containin...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q7Z7D3-1.
TMPY-03009 B7-H4 Protein, Human, Recombinant (hFc)

B7h.5,B7X,PRO1291,B7S1,B7H4,B7-H4...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1.
TMPY-05281 B7-H4 Protein, Human, Recombinant (His), Biotinylated

PRO1291,VCTN1,B7S1

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPY-05280 B7-H4 Protein, Human, Recombinant (hFc), Biotinylated

B7S1,B7X,VCTN1,B7h.5,V-s...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1.
TMPY-05611 B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated

PRO1291,B7X,V-set domain containi...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.6 kDa and the accession number is Q7Z7D3-1.
TMPY-02208 Peroxiredoxin 5 Protein, Human, Recombinant (His)

B166,HEL-S-55,prx-V,ACR1,PMP20,AO...

Human E. coli
Peroxiredoxin 5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.5 kDa and the accession number is P30044-2.
TMPJ-00176 B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated

B7H4T-cell costimulatory molecule B7x,FLJ22418,B7XP...

Human HEK293 Cells
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine ...
TMPJ-00175 B7-H4 Protein, Rhesus macaque, Recombinant (hFc)

V-set domain containing T cell activation ...

Rhesus HEK293 Cells
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the s...
TMPJ-01100 UBE2V1 Protein, Human, Recombinant (His)

TRAF6-Regulated IKK Activator 1 Beta Ue

Human E. coli
Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inactive on its own. However, in the cytoplasm UBE2V1 is able to form a catalytically active complex with UBE2N/Ubc13, which mediates the synthesis Lys63-linked Ubiquitin chains and is required for NF-kappa B activation. UBE2V1 is required for UBE2N (Ubc13)/UBE2V1 Complex-dependent Ly...
TMPY-04622 PF4V1 Protein, Human, Recombinant (mFc)

PF4A,CXCL4V1,platelet factor 4 va...

Human HEK293 Cells
PF4V1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.6 kDa and the accession number is P10720.
TMPY-04137 ATP6V1F Protein, Human, Recombinant (GST)

Vma7,ATPase, H+ transporting, lysosomal 14...

Human E. coli
ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using reverse transcription polymerase chain reaction and touchdown-polymerase chain reaction, respectively. Topology prediction showed that there is one protein kinase C phosphorylation site, two Casein kinase II phosphorylation sites, and one N-myristoylation site in the ATP6V1F protein. U...
TMPH-02403 JBP1 Protein, Leishmania infantum, Recombinant (His & V5)

Leishmania infantum E. coli
JBP1 Protein, Leishmania infantum, Recombinant (His & V5) is expressed in E. coli expression system with N-10xHis-V5 tag. The predicted molecular weight is 53.4 kDa and the accession number is A4HU70.
TMPJ-00849 ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)

Protein ST2,IL-1 R4,IL-33R,ST2V,suppressio...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2.
TMPY-01801 c-Kit Protein, Mouse, Recombinant (hFc)

SCO1,Gsfsco1,W,v-kit Hardy-Zucker...

Mouse HEK293 Cells
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.5 kDa and the accession number is P05532-1.
TMPY-06079 SARS-CoV-2 Spike S1 Protein (A222V & D614G, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (A222V & D614G, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06413 SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.28 kDa and the accession number is A0A6G7K2L4.
TMPY-06399 SARS-CoV-2 Spike S1 Protein (E484K & F565L & D614G & V1176F, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (E484K & F565L & D614G & V1176F, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.37 kDa and the accession number is A0A6G7K2L4.
TMPY-05713 SARS-CoV-2 Spike S1+S2 ECD Protein (R683A & R685A & K986P & V987P, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 ECD Protein (R683A & R685A & K986P & V987P, His) is expressed in Baculovirus insect cells. The predicted molecular weight is 135.37 kDa and the accession number is A0A6G7K2L4.
TMPY-06398 SARS-CoV-2 Spike S1+S2 Protein (E484K & F565L & D614G & V1176F, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (E484K & F565L & D614G & V1176F, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.35 kDa and the accession number is A0A6G7K2L4.
TMPY-06437 SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.20 kDa and the accession number is A0A6G7K2L4.
TMPY-06305 SARS-CoV-2 Spike S1 Protein (Q52 & A67V & 69-70 deletion & 144 deletion & E484K & D614G & Q677H, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (Q52 & A67V & 69-70 deletion & 144 deletion & E484K & D614G & Q677H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.07 kDa and the accession number is A0A6G7K2L4.
TMPY-06132 SARS-CoV-2 Spike S1+S2 Protein (D80A & K417N & E484K & N501Y & D614G & A701V, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (D80A & K417N & E484K & N501Y & D614G & A701V, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06396 SARS-CoV-2 Spike S1 Protein (G75V & T76I & 246-252 deletion & D253N & L452Q & F490S & D614G, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (G75V & T76I & 246-252 deletion & D253N & L452Q & F490S & D614G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 75.64 kDa and the accession number is A0A6G7K2L4.
TMPY-06393 SARS-CoV-2 Spike S1+S2 Protein (L5F & T95I & D253G & S477N & E484K & D614G & A701V, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L5F & T95I & D253G & S477N & E484K & D614G & A701V, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.34 kDa and the accession number is A0A6G7K2L4.
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重组蛋白

B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06074
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
Art v 1 Protein, Artemisia vulgaris, Recombinant (His)
Cat.No: TMPY-05525
Species: Artemisia vulgaris
Expression System: HEK293 Cells
Bet v 1-A Protein, Betula pendula, Recombinant (His & SUMO)
Cat.No: TMPH-00199
Species: Betula pendula
Expression System: E. coli
AKT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
B7-H4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05322
Species: Mouse
Expression System: HEK293 Cells
ATP6V0D1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02310
Species: Human
Expression System: E. coli
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
VISTA Protein, Human, Recombinant (His)
Cat.No: TMPY-03219
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03524
Species: Human
Expression System: HEK293 Cells
VNN1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02529
Species: Mouse
Expression System: HEK293 Cells
VNN1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02730
Species: Mouse
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
c-Kit Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01802
Species: Mouse
Expression System: HEK293 Cells
EVA-1/MPZL2 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00737
Species: Human
Expression System: HEK293 Cells
EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00738
Species: Mouse
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00377
Species: Human
Expression System: HEK293 Cells
VSTM1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02563
Species: Human
Expression System: HEK293 Cells
VSTM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02555
Species: Human
Expression System: HEK293 Cells
ALDH1A3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06352
Species: Mouse
Expression System: E. coli
B7-H4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02658
Species: Mouse
Expression System: HEK293 Cells
ETS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00854
Species: Human
Expression System: E. coli
NRAS Protein, Human, Recombinant (His)
Cat.No: TMPY-03487
Species: Human
Expression System: E. coli
VISTA Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00501
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05184
Species: Human
Expression System: HEK293 Cells
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06894
Species: Human
Expression System: HEK293 Cells
PRDX5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00933
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05080
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03009
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05281
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05280
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05611
Species: Human
Expression System: HEK293 Cells
Peroxiredoxin 5 Protein, Human, Recombinant (His)
Cat.No: TMPY-02208
Species: Human
Expression System: E. coli
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPJ-00176
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00175
Species: Rhesus
Expression System: HEK293 Cells
UBE2V1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01100
Species: Human
Expression System: E. coli
PF4V1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04622
Species: Human
Expression System: HEK293 Cells
ATP6V1F Protein, Human, Recombinant (GST)
Cat.No: TMPY-04137
Species: Human
Expression System: E. coli
JBP1 Protein, Leishmania infantum, Recombinant (His & V5)
Cat.No: TMPH-02403
Species: Leishmania infantum
Expression System: E. coli
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)
Cat.No: TMPJ-00849
Species: Mouse
Expression System: HEK293 Cells
c-Kit Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01801
Species: Mouse
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (A222V & D614G, His)
Cat.No: TMPY-06079
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06413
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (E484K & F565L & D614G & V1176F, His)
Cat.No: TMPY-06399
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 ECD Protein (R683A & R685A & K986P & V987P, His)
Cat.No: TMPY-05713
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (E484K & F565L & D614G & V1176F, His)
Cat.No: TMPY-06398
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T19R & V70F & E156G & 157-158 deletion & A222V & K417N & L452R & T478K & D614G & P681R & D950N, His)
Cat.No: TMPY-06437
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (Q52 & A67V & 69-70 deletion & 144 deletion & E484K & D614G & Q677H, His)
Cat.No: TMPY-06305
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (D80A & K417N & E484K & N501Y & D614G & A701V, His)
Cat.No: TMPY-06132
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (G75V & T76I & 246-252 deletion & D253N & L452Q & F490S & D614G, His)
Cat.No: TMPY-06396
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (L5F & T95I & D253G & S477N & E484K & D614G & A701V, His)
Cat.No: TMPY-06393
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
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